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NEW YORK – RoC has unveiled the results of its largest clinical study yet: RoC 35. Centered around helping women gain positive perceptions of self, including optimism about the condition of their skin, this landmark study honors RoC Skincare’s French pharmacy roots via partnership with 35 clinics across France with specialties in plastic surgery, aesthetics, and dermatology.
Following the RoC 35 skincare protocol, participants aged 45+ report their skin looking and feeling, on average, 9.6 years younger after only 90 days of use. This innovative regimen, combining five powerful products and four key molecules, helps women align their skin’s visible age with the way they feel, empowering them to embrace aging while boosting their emotional confidence.
The RoC 35 Protocol features a comprehensive five-product morning and evening routine: two serums (Firming Serum Stick and Revive + Glow), two moisturizers (Firm + Lift and Hydrate + Plump), and an eye cream (Dual Eye Cream). This lineup incorporates RoC’s star molecules: Retinol, Hyaluronic Acid, THPE, and Vitamin C, working synergistically to deliver maximum skin rejuvenation.
Over 200 patients followed the RoC 35 protocol with no other skincare products and under healthcare professional supervision. A full-face medical skin checkup was conducted at the start, 30 days, and 90 days into the protocol to screen for the most critical 30 signs of aging, with supplemental measurement of skin improvements via Visia’s professional image system.

“RoC has been a pioneer in retinol innovation for over thirty years, and it remains at the foundation of the RoC 35 program,” says Art Pellegrino, Chief Scientific Officer at RoC Skincare. “With innovative stabilization methods, we found that results from RoC’s retinol won’t plateau over a year’s time and it can be used with vitamin C on the same day which is rare due to the high potency of this ingredient.”
Benoit Chardon, director of the RoC 35 study, adds, “Our goal is to simplify skincare, making it easier for consumers to achieve transformative results. By leveraging insights from this extensive research, RoC aims to empower physicians and consumers with the knowledge needed to build a product routine for preventative aging, with the right ingredients at the right time of the day, reinforcing its mission to make science-driven skincare accessible to all.”
Thirty key parameters of youthful skin improved, including:
● Healthy, Glowing, Even Skin: 98% of patients reported more radiant, healthy, and even skin tone.
● Smooth & Hydrated Skin: 97% of patients experienced softer, more hydrated skin with less visible pores.
● Firm & Lifted Skin: 90% of patients noticed firmer, plumper, more elastic skin with a feeling of lift.
● Wrinkle Reduction: 91% of patients saw an improvement in the appearance of superficial, medium, and deep wrinkles on the face and neck.
● Eye Contour Improvement: 92% of patients observed improvements in eye bags, dark circles, and crow’s feet, resulting in a more rested, youthful, and smoother look.
● Emotional Boost: 90% of patients felt their skin looked younger, rested, and revitalized, leading to increased confidence and optimism.
Key study findings include:
- 98% of participants reported a healthier, glowing, and even skin tone.
- 97% experienced smoother, hydrated skin with less visible pores.
- 90% saw firmer, plumper skin, with noticeable lifting.
- 91% saw improvements in superficial, medium, and deep wrinkles.
- 92% experienced visible improvement in eye contours, reducing dark circles and crow’s feet.
- 90% reported an emotional boost, feeling more confident and optimistic about their skin.