SEATTLE —Amazon One Medical now offers weight loss care through two distinct options: insurance-covered visits with primary care integration in regions with One Medical offices, and cash-pay, on-demand virtual care via direct message (where applicable) or video care, now available in 48 states and Washington, D.C.
Obesity affects more than 40% of U.S. adults and contributes to nearly $173 billion in annual medical costs. Despite medical advances like GLP-1 therapies, patients often face fragmented care with unclear or surprise costs for medication.
Amazon One Medical addresses these challenges by giving patients more choice in how they access clinically supervised weight loss care—from primary care to the newly expanded cash-pay virtual option—alongside transparent pricing through Amazon Pharmacy.
Here’s how it works.
How does One Medical's existing GLP-1 management program work?
The existing program, launched in April, integrates GLP-1 management into patients' broader primary care relationship, proactively managing how weight loss intersects with cardiovascular health, metabolic conditions, and overall health. Available in regions with a One Medical office, patients benefit from a fully integrated care journey: pre-visit screening, structured consultations, regular follow-up visits with integrated monitoring, standardized documentation, and evidence-based treatment with built-in safety protocols.Sustainable weight loss isn't just about medication—it’s about treating obesity as a chronic condition that requires ongoing medical supervision. The integrated approach means clinicians can monitor progress, adjust treatments, and address related health conditions like cardiovascular disease and diabetes, all as part of a patient's primary care relationship. Early feedback from clinicians and patients has been positive about this integrated approach.
One Medical clinicians work with patients to send prescriptions to the pharmacy of their choice. For patients who choose Amazon Pharmacy, the integration provides upfront, transparent medication costs, even before booking an appointment, along with same- and next-day prescription delivery. Medication is also available for pickup in select Amazon Kiosks, within One Medical offices.The program is available now at Amazon One Medical locations across the U.S. One Medical membership is not required to get started or to schedule a visit.One Medical accepts most major insurance plans for scheduled in-person and video visits, including GLP-1 Management Program visits. Copays and deductibles may apply if billed to insurance.
How does on-demand GLP-1 virtual care work?
For patients who don’t use One Medical for primary care and prefer a virtual cash-pay option, Amazon One Medical also offers on-demand care—24/7 telehealth for GLP-1 weight loss care through direct message care (where available) or video care. The service is now available in 48 states and Washington, D.C., starting from $39 for direct message care and $59 for video care. Cost of medications is separate from the cost of the visit and does not include prior authorization support.Designed for individuals who prefer to pay out-of-pocket for their weight loss care, the program offers a transparent, pay-as-you-go option with no insurance required.Here’s how the process works:
- Patients complete a health screening and provide a copy of their most recent labs for a clinician to review and confirm that GLP-1s are safe for them.
- A licensed clinician evaluates the patient through a direct message (where applicable by state) or video care.
- If clinically appropriate, the provider can write a prescription during that same interaction.
- Patients can follow up with their provider within 14 days of their initial visit with any questions or concerns.
When patients are ready to increase their dosage or are running low on medication, they can return and start a new visit.On-demand care is focused specifically on weight loss evaluation and prescribing. Unlike the One Medical primary care experience—where GLP-1 management is integrated into a patient's broader primary care relationship, health records, and ongoing monitoring across conditions—on-demand care is a standalone service for individuals seeking a straightforward, affordable entry point to GLP-1 treatment.Following a small direct message care pilot, on-demand care has maintained high customer satisfaction rates. Customer feedback highlights the speed and convenience of connecting with a provider and getting a prescription renewed, as well as the affordability of the service and ability to see medication costs upfront through Amazon Pharmacy.
GLP-1 medications through Amazon Pharmacy
Amazon Pharmacy makes GLP-1 medications more accessible with transparent pricing and convenient delivery options. The pharmacy now offers the newly FDA-approved Wegovy and Foundayo oral GLP-1 pills for weight management—with insurance coverage starting as low as $25 per month or cash-pay options starting at $149 per month for both oral medications.Amazon Pharmacy also provides Wegovy injectables, Zepbound auto-injector, and KwikPen—a multi-dose injectable delivering a full month of medication in a single device—with cash-pay pricing starting at $199 per month. All medications are available for fast delivery to all 50 states, with Same-Day Delivery to nearly 3,100 cities and towns today and expanding to nearly 4,500 by the end of 2026.
Providing customers with fast, convenient medication access and clear, transparent pricing is integral to how Amazon Pharmacy is transforming the pharmacy experience," said Tanvi Patel, vice president and general manager of Amazon Pharmacy. "By expanding access to the latest GLP-1 medications with upfront, clear pricing, we're making it easier for customers to get the treatments their health care providers prescribe and to stay on those medications because they are delivered reliably directly to patients.”Patients using One Medical insurance-based GLP-1 management can compare insurance and cash-pay prices side-by-side. Certain manufacturer coupons will also be automatically applied to eligible customers at checkout. To date, Amazon Pharmacy customers have saved over $400 million through the automatic coupon program.By offering multiple options across 48 states for weight loss care, Amazon is removing the geographic and financial barriers that make weight management feel overwhelming and making it easier for patients to access comprehensive, connected care to achieve their health goals.Next, learn more about Amazon’s Health AI agent, which can answer your medical questions, explain health records, manage prescription renewals, book appointments, and more.
